A Windows GUI application for real-time image guidance during motion- managed proton beam therapy

Respiratory motion-management is crucial for maintaining robustness of the delivered dose in radiotherapy. This is particularly relevant for spot-scanned proton therapy, where motion-induced dosimetric “interplay” effects can severely perturb the …

Image-guidance Software Development

In order to facilitate better clinical workflow and provide added assurance during motion-managed proton therapy delivery, I am developing a clinical computer vision application (Code name: Wukong), based on high-speed acquisition and real-time processing of fluoroscopic frames. Built as a fully DICOM-aware utility, this .NET/C# Windows desktop application is integrated into existing treatment planning infrastructure, both for treatment plan information communication and permanent data archival on a HIPAA-compliant cloud storage.

Flat-panel Detector Calibration

Accurate delivery of radiotherapy dose is predicated upon careful motion management. This is particularly true for spot-scanned proton therapy. Our proton therapy vendor developed a stereoscopic kV X-ray image-guidance platform for this purpose. While it is engineered to a given specification, the actual positions of the components (e.g. flat-panel detectors) may contain small errors. This project delivers an iterative algorithmic calibration routine to correct such errors, i.e. translation, rotation and non-affine distortions. The main motivation behind this routine is to enable high-fidelity perspective overlays of RT structure sets in our in-house clinical software. It may also be used as an independent QA of vendor's own calibrations.